Combining TCE exposure with ethanol is known to produce which effect?

Combining trichloroethylene (TCE) exposure with ethanol creates a physiological reaction known as "degreaser's flush." This occurs because the presence of ethanol can inhibit the metabolism of TCE in the liver, leading to the accumulation of toxic metabolites that cause flushing, a rapid reddening of the skin due to increased blood flow. This is particularly common in individuals who are exposed to solvents like TCE in degreasing operations and also consume alcohol, resulting in an unpleasant reaction.

This information highlights the importance of understanding the interactions between environmental exposures and lifestyle choices, particularly for workers in industrial settings. This awareness can help in implementing safety measures and making informed decisions regarding alcohol consumption in environments where chemical exposure is prevalent.