What major organ systems are affected by arsine exposure?

Arsine is a highly toxic gas that is primarily associated with specific adverse effects on the vascular system, kidneys, and liver. When inhaled, arsine can lead to hemolysis, which is the destruction of red blood cells, contributing to a significant impact on the vascular system by reducing the ability to transport oxygen throughout the body. Additionally, arsine exposure can result in renal failure due to its nephrotoxic effects, affecting the kidneys' functionality and leading to potential systemic complications. The liver is also affected as it is vital in metabolizing and detoxifying various substances, including toxicants, hence exposure can lead to hepatotoxic effects.

This understanding of the effects of arsine exposure underscores the importance of monitoring and enforcing safety protocols in environments where arsine may be present, particularly concerning workers in industries like semiconductor manufacturing and metallurgy, where arsenic and its compounds are used.