What type of irritation is primarily associated with exposure to phosgene?

Exposure to phosgene is primarily associated with mucous membrane and skin irritation due to its chemical properties as a highly toxic gas that can cause significant damage to the respiratory system. When inhaled, phosgene can lead to severe inflammation and irritation of the mucous membranes lining the lungs, throat, and eyes. This irritation may manifest as coughing, difficulty breathing, and the sensation of burning or irritation in the eyes and throat.

While phosgene can affect various body systems, gastrointestinal irritation, cardiovascular issues, and neurological effects are not the primary concerns associated with this chemical. Phosgene’s most notorious effects are related to respiratory distress and injury, which occur when it interacts with the mucous membranes. Therefore, focusing on the initial irritative effects when exposed to this substance is crucial for understanding its health risks.