Which toxic substance is associated with lesions in the respiratory system and is rapid in skin absorption?

The correct answer is tetraethyl lead. This substance is known for its potential to cause significant respiratory system lesions and is also characterized by its rapid absorption through the skin. Tetraethyl lead, traditionally used in gasoline, can lead to lead poisoning when inhaled or absorbed, resulting in severe health effects.

The mechanism of toxicity primarily arises from lead's ability to interfere with various biochemical processes, particularly in the nervous system and other organ systems. When it enters the body, it can cause inflammation and damage in the respiratory tract, which can manifest as lesions and other respiratory ailments.

In contrast, while methyl ethyl ketone, antimony, and benzidine each have their own toxicological profiles, they do not share the same rapid skin absorption characteristics and specific respiratory lesion links that are prominent with tetraethyl lead. Understanding these properties is crucial for industrial hygienists who seek to mitigate exposure to harmful substances in occupational settings.